Abstract
We designed a longitudinal study to investigate brain maturation in preterm infants, using the Assessment of Preterm Infant's Behavior(APIB), MRI(GW;M), MRS(NAA/Cho), Dubowitz scale(D) for neurologic assessment and brainstem auditory evoked potentials(BAEP:V). Age-dependent maturational changes are presented in the first six patients, studied at a mean gestational age(GA) of 32.7±1.4 weeks and again at due date(mean GA:40.1±1.3w).
Conclusion: First results indicate, that grey-while matter differentiation and myelination in MRI clearly discriminates maturational stages in brain development followed by MRS, behavioral studies assessed in autonomic-, motoric organization, self-regulation and examiner facilitation, neurologic assessment and BAEP.
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Hüppi, P., Schuknechi, B., Donali, F. et al. 46 BRAIN DEVELOPMENT IN PRETERM INFANTS studied by MRI, MRS, APIB, Dubowitz scale and BAEP. Pediatr Res 30, 635 (1991). https://doi.org/10.1203/00006450-199112000-00076
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DOI: https://doi.org/10.1203/00006450-199112000-00076