Abstract
VD has been related with poor prognosis in VLBW. Cerebral ultrasound were prospectively performed in 100 babies≤ 1500g in order to evaluate the prognostic significance of VD and their associated findings. 77 babies were followed up until 18 months. Of the total, 24% developed VD, it not being differences in its incidence between patients with or without periventricular hemorrhage(PVH). In patients with PVH,VD developed earlier than in infants without PVH(p<0.05). However, there were no differences according to severity, location, head circumference growth or intracranial pressure. Lumbar taps were performed in 4 patients (all with PVH). VD was statistically associated with:PVH grades III and IV(p=0.015); periventricular (PV) hyperdensity (moderate and severe) (p<0.001); and cystic periventricular leukomalacia (PVL) (p=0.0023) .6l% of VD lasted > 6 wk (persistent) and showed irregular margins in 62%. The latter were significantly related with cystic PVL (p=0.017). At follow up, VD was statistically associated with handicaps but specially the persistent VD with irregular margins. We conclude that VD is frequent in VLBW infants, many times independent from PVH and even in its mild forms, those with persistent VD with irregular margins suggest PV parenchymal lesion and reserved prognosis, as their association with echographic signs of PVL are demonstrated.
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Pellicer, A., Cabañas, F., Garcia-Alix, A. et al. 17 NETURAL HISTORY OF VENTRICULAR DILATION (VD) IN PRETERM BABIES, PROGNOSTIC SIGNIFICANCE. Pediatr Res 30, 631 (1991). https://doi.org/10.1203/00006450-199112000-00047
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DOI: https://doi.org/10.1203/00006450-199112000-00047