Abstract
In 175 high risk neonates (87:>2500 g; 50:2500–1500 g; 38: <1500 g) cerebral blood flow velocities (CBFV)were measured by transcranial Doppler in the basal cerebral arteries on the 1st, 3rd to 5th and 8th to 10th day of life. They were compared with values of healthy neonates. Cranial ultrasound was performed on all babies. On the 1st day 66% of the babies had normal, 23% decreased, and 12% increased CBFV. On day 8 to 10 87% had normal, 6% decreased, and 7% increased CBFV. In babies below 1500 g, normal CBFV were associated with the lowest incidence of cerebral hemorrhage (h) and death (d) (6/23 h; no d) while increased CBFV indicated poor prognosis (8/12 h; 7/12 d). Babies with decreased CBFV showed more hemorrhages and deaths than those with normal CBFV. A similar incidence of hypoxic ischemic encephalopathies, hemorrhages and deaths was found in neonates more than 1500 g with both normal or abnormal CBFV. Conclusion: CBFV measured by Doppler are useful as an early prognostic parameter in infants below 2500 g; in higher birth weights they may be useful for prognosis only in selected cases.
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Das-Kundu, S., Bode, H. & Nars, P. 15 CERBRAL BLOOD FLOW VELOCITY IN THE HIGH RISK NEWBORN – AN INDICATOR OF EARLY PROGNOSIS. Pediatr Res 30, 630 (1991). https://doi.org/10.1203/00006450-199112000-00045
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DOI: https://doi.org/10.1203/00006450-199112000-00045