Abstract
Free fatty acid (FFA), triglyceride (TG), cholesterol (C), VLDL+LDL-C, HDL-C and its subfractions were determined in 18 very low birthweight preterm infants (birthweight:1064±179 g, gestational age; 28.7±1.6 weeks, mean±SD) on postnatal Days 1, 14, 28, 42 and 56. TG and C were measured enzymatically, FFA by colorimetric, whereas HDL-C and its subfractions by microprecipitation methods (data are in mmol/l). TG levels increased significantly from Day 1 to 14 and from 14 to 28 (0.61±0.26 vs 1.14±0.28 va 1.70±0.89, p < 0.02), thereafter remained unchanged. C levels increased up to Day 28 (Day 1:2.29±0.83, Day 14:3.05±0.71, Day 28:3.34±1.58, Day 1 vs Day 14 p< 0.01), thereafter decreased to the level of Day 1 (Day 56: 2.63±0.87). In absolute values more marked alterations were seen in the VLDL+LDL-C fraction (Day 1: 1.51±0.70, Day 28:2.32±1.34, Day 56:1.76±0.74), whereas within HDL-C it was HDL2-C which changed significantly. The alterations observed were similar to those seen in term infants; the time course of the events, however, proved to be different.
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Decsi, T., Molnár, D. & Klujber, L. LIPID LEVELS IN VERY LOW BIRTHWEIGHT PRE-TERM INFANTS:BIWEEKLY FOLLOW-UP DURING THE FIRST EIGHT WEEKS OF LIFE. Pediatr Res 26, 514 (1989). https://doi.org/10.1203/00006450-198911000-00092
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DOI: https://doi.org/10.1203/00006450-198911000-00092