We compared epidemiologic and clinical features of Kawasaki Syndrome (KS) in 110 pts aged 2 wks to 12 9/12 yrs and seen Jan '80 to Aug '86 with large series from Japan. Similarities: age below 5 yrs (72%), sex (61% male), urban and suburban dwelling almost entirely, recurrence rate (2%), myocardial infarction (1%), and death rate (1%). Incidence of coronary aneurysms (18%) was associated in both areas with duration of fever (≥4 days) and in NY with Oriental race and height of platelet count. Yearly seasonal incidence was highest in springtime, as in Japan during epidemics.

Dissimilarities: Heterogeneity in NY (50% Caucasian, 18% Black, 16% Hispanic, 16% Asian); mean age in NY (3½ yrs) higher than in Japan (1½h yrs); 32% <2 yrs in NY vs 50-60% in Japan; higher incidence of clinically apparent acute myocarditis (8%), but lower incidence of late cardiac failure (1%) and valvular regurgitation (2%) in NY.

Personal interview with 60 families revealed use of rug shampoo within 1 month of onset in 12 (20%) and 1 case of recurrence after 2nd shampoo. This was the only family with 2 siblings affected, 1 wk apart.

We conclude that KS in a heterogeneous Manhattan population resembles KS in Japan except for age distribution. In NY it occurred more often and more severely in Asians than in non-Asians.

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Fatica, N., Ichida, F., Engle, M. et al. EPIDEMIOLOGIC ASPECTS OF KAWASAKI SYNDROME IN MIDMANHATTAN AND IN JAPAN. Pediatr Res 21, 190 (1987). https://doi.org/10.1203/00006450-198704010-00141

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