Up to date most pubblished reports on ICS refer to clinical picture without any distinction between symptoms and complications observed when diagnosis is performed.
In a series of 12 ICS pts patterns and time of onset of symptoms and of organ system related complications have been established.
Nasal dropping and cough were prevalent from birth followed by bronchitis, recurrent otitis and lung infections.
Serous otitis and synusitis were the most early and frequent complications.
Nasal polyps, bronchiectasis, segmental/lobar atelectasis, hear loss and anosmia were less frequent and more late.
A detailed clinical feature is usefull for early diagnosis expecially in those pts without situs viscerum inversus.
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Antonelli, H., Bertasi, S., Di Paolo, A. et al. CHRONOLOGY OF SYMPTOMS AND COMPLICATIONS OF IMMOTILE CILIA SYNDROME (ICS). Pediatr Res 19, 1093 (1985) doi:10.1203/00006450-198510000-00147