Abstract
There are limited data on cardiac function in premature infants. Computer-determined instantaneous velocities of the left ventricular (LV) minor axis provide estimates of systolic and diastolic function. We determined the LV Maximal Velocity of Shortening(MVS) and Maximal Velocity of Lengthening(MVL) for 32 neonates of various gestational ages(GA) within the first three days of life. Infants with Congenital Heart Disease. Patent Ductus Arteriosus(PDA), asphxia, or sepsis were excluded from the study, x±S.D. were:
Conclusions 1)The data indicate developmental differences in systolic and diastolic cardiac function and support experimental evidence for differences in contractility and compliance in the immature heart. 2)These parameters may prove useful in studying the effects of hemodynamic loads such as a PDA on cardiac function in the critically ill premature infant.
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Appleton, R., Graham, T., Cotton, R. et al. 75 DEVELOPMENTAL DIFFERENCES IN CARDIAC FUNCTION IN HUMAN NEONATES. Pediatr Res 19, 123 (1985). https://doi.org/10.1203/00006450-198504000-00105
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DOI: https://doi.org/10.1203/00006450-198504000-00105