Abstract
Sixteen episodes of priapism in 6 children with SCD, aged from 9 to 15 years (mean 12.0 ± 2.5) were treated with 2 or 3 PET. In 14 episodes (4 patients) PET was started within 6 to 8 hours from the onset. Marked clinical improvement occurred within 1.3 ± 0.5 days and complete recovery followed each episode. In 2 episodes (2 patients) PET was started at 17 and 20 hours from the onset. In these 2 cases there was only partial response to PET and needle aspiration of corpora cavernosum and glandular A-V fistula were performed at the 3rd and 5th day of the onset, respectively.
Priapism is a serious complication of SCD and may result in impotence. Conservative measures generally are not effective and impotence (partial or complete) is a frequent sequal to surgical procedures. Treatment with PET is successful alternative therapy at the early onset of priapism.
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Karayalcin, G., Shende, A., Festa, R. et al. PARTIAL EXCHANGE TRANSFUSION (PET) FOR TREATMENT OF PRIAPISM IN CHILDREN WITH SICKLE CELL DISEASE (SCD). Pediatr Res 18 (Suppl 4), 242 (1984). https://doi.org/10.1203/00006450-198404001-00897
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DOI: https://doi.org/10.1203/00006450-198404001-00897