Abstract
Of 569 oxygen-treated neonates examined by two retinologists between 1/75 and 12/79, 50 had RLF. The severest grade in either eye is indicated in Table I. A comparison of the duration of exposure to several PaO2 levels was made between RLF neonates and 50 weight-matched controls without RLF. Linear trending of the PaO2 between individual PaO2 determinations was assumed in order to estimate the time each patient was exposed to a given PaO2 range. Only the period when arterial blood gases were obtainable from indwelling catheters was analyzed. Short periods of exposure to high PaO2's do not seem to have a significant relationship to the genesis of RLF. However, even modestly elevated PaO2's (80-99) for significant durations may influence RLF development.
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Satish, M., Katzman, G., Krishnan, V. et al. 1415 STUDIES IN RETROLENTAL FIBROPLASIA (RLF) I – ASSOCIATION OF ARTERIAL PaO2.. Pediatr Res 15 (Suppl 4), 679 (1981). https://doi.org/10.1203/00006450-198104001-01444
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DOI: https://doi.org/10.1203/00006450-198104001-01444