Abstract
A turkish boy was referred at age 41 days for convulsions. Clinical and radiologic examination showed marked features of rickets. Serum calcium (Ca) and phosphorus (P) concentrations were 1.74 and 1.66 mmo1/1 respectively and alkaline phosphatase 2388 IU/1. Serum immunoreactive PTH concentration was > 400 μ1Eq/ml (N < 100) and serum i Calcitonin concentration was normal ( < 150 pg/ml). Plasma 25 hydroxycholecalciferol (25 OH CC) concentration was < 10 nmo1/1 (N : 25-80). Hypocalcemia and rickets were cured by Ca supplementation, 1300 μg of 25 OH CC and 200 000 IU of vitamin D3. His mother has low serum Ca : 1.60 mmo1/1 and non detectable plasma 25 OH CC concentrations.
These data suggest that this early rickets was from maternal origin.
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Sann, L., Rousson, R., Frederich, A. et al. SEVERE RICKETS IN A 41 DAY OLD TURKISH BOY DUE TO MATERNAL VITAMIN D DEFICIENCY. Pediatr Res 14, 1418 (1980). https://doi.org/10.1203/00006450-198012000-00061
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DOI: https://doi.org/10.1203/00006450-198012000-00061