Abstract
This retrospective study evaluated the differences and outcome of children ≤6 mos. of age admitted with the diagnosis of fever, possible sepsis and apnea; none with foci of serious infection. There were 44 pts. in Gp. A (bacterial negative disease), 6 in Gp. B (bacterial proven disease), 5 in Gp. C (latent disease) and 17 in Gp.D (apnea). Historical information obtained: age, admission temperature, preadmission duration of illness, incidence of GI or URI symptoms, and concurrent family illness. Lab data included: weight, CBC, chest x-ray, CSF analysis, blood cultures and urinalysis and culture. Mean age was Gp. A: 7.1 wks, Gp. B: 13.2 wks, Gp. C: 17.2 wks, Gp. D: 7.8 wks. Mean temperature was similar in gps. A thru C (38.6°C, 39°C, 39.4°C). Pre-admission duration of illness was longer in Gps. B & C. There was no concurrent family illness in Gp. B, vs. 50% in Gp. A. Absolute band counts did not correlate with bacterial disease; 1400/m3 in Gp. A, 900/m3 in Gp. B, 2800/m3 in Gp. C. Absolute neutrophil counts (ANC) were more reliable; Gp. A: 4700/m3, Gp. B: 7600/m3. Discharge diagnoses in Gp. B included 2 UTIs and 4 episodes of sepsis. Gp. A included viral illness (21), URI (6), fever (5), gastroenteritis (4) and others. Gp.C included aseptic meningitis (1), otitis media (2), viral pneumonia (2); all developing after admission. Gp. D included apnea (13), URI (4). The incidence of proven bacterial disease was 8.3% and significant differences in age, preadmission duration of illness, concurrent family illness and ANC were noted.
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Muido, L., Weiner, L. & Oski, F. 369 FEVER AND PRESUMED SEPSIS IN INFANTS < 6 MOS. OF AGE. Pediatr Res 12 (Suppl 4), 425 (1978). https://doi.org/10.1203/00006450-197804001-00374
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DOI: https://doi.org/10.1203/00006450-197804001-00374