Abstract
The response of the interventricular septum(IVS) and the left ventricular(LV) posterior wall(PW) to LV volume overload was evaluated by echocardiography in 22 patients(pts.) with ventricular septal defect (Qp:Qs>2:1)(Group A) and 8 pts. with isolated mitral regurgitation(LA/AO> 1.5:1)(Group B). Both groups were compared to 47 normals ranging in age from one month to 16 years(Group C). Excursions(E) of IVS and PW were measured as the vertical length of maximal posterior motion of IVS and maixmal anterior motion of PW at the level of posterior mitral valve, respectively. Following parameters were calculated :(1)Septal fractional shortening(SFS)=IVSE/LV end-diastolia dimension(Dd), (2)Posterior wall fractional shortening(PFS)= PWE/Dd and (3)Ratio of SFS to PFS.
These data show that PW normally is the major dynamic component of LV contraction. With LV volume overload IVS becomes hyperdynamic and accounts for the apparent increase in the contractility of LV even with the presence of a hypodynamic LV posterior wall.
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Lee, DH., Varehese, P., Shematek, J. et al. 129 DYNAMIC ALTERATION OF THE INTERVENTRICULAR SEPTUM IN VOLUME OVERLOAD OF THE LEFT VENTRICLE. Pediatr Res 12 (Suppl 4), 385 (1978). https://doi.org/10.1203/00006450-197804001-00134
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DOI: https://doi.org/10.1203/00006450-197804001-00134