Abstract
The risk potential of isolated prenatal or perinatal event is often inadequate and misleading in the prediction of long term prognosis. In order to assess the value of cumulative prenatal and perinatal factors as they relate to outcome, 42 infants (B.Wt. >1500 G) who received ventilatory assistance (VA) neonatally were compared to 42 non-ventilated matched controls (C). Matching variables were race, sex, gestational age and birth weight. Prenatal, paranatal and postnatal factors cumulatively were evaluated in conjunction with physical, neurological, audiological, opthalmological developmental assessments in the VA and C infants at 1 yr. of age. The VA infants had significantly higher incidence of prolonged rupture of membranes, second and third trimester bleeding, stained amniotic fluid, lower Apgar scores, seizures, congenital heart disease, RDS, apnea, infection and blood transfusions associated with abnormal physical, neurological and developmental findings. Cumulative prenatal and perinatal data were arranged in a discriminating function and predicted whether or not the infant will require VA in 85% of cases. Multiple factors obtained cumulatively in the prenatal, paranatal and postnatal periods may be more useful in evaluation of risk factors for long term prognosis.
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Teberg, A., Wu, P., Azen, S. et al. 74 ONE YEAR FOLLOW-UP OUTCOME OF VENTILATORY ASSISTED INFANTS (B.Wt. >1500G) CORRELATED WITH PRENATAL AND PERINATAL FACTORS. Pediatr Res 12 (Suppl 4), 376 (1978). https://doi.org/10.1203/00006450-197804001-00079
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DOI: https://doi.org/10.1203/00006450-197804001-00079