Abstract
40 hyperthyroid children were followed for 0.2-12 (mean 4.5) years. The treatment was antithyroid drugs in 20 (Group I), thyroidectomy after a drug trial in 18 (IIa), and primary thyroidectomy in 2 (IIb). 4 patients relapsed after surgery and were given radioiodide. Half of the operated glands were nodular. At the follow-up study, of Groups I and II, 17 and 7 patients were euthyroid, none and 12 hypothyroid, and 2 on continuing medication and 1 relapsed, respectively. 3 and 2 of the euthyroid patients had decreased thyroid reserve. The gastric mucosa was abnormal in 7 of the 27 patients who were studied. 2 were achlorhydric and 12 had parietal cell antibodies. Circulating antibodies against thyroid microsomes were present in 31 of 34 patients. Evidently, follow-up is needed because of the immunological abnormalities.
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Mäenpää, J., Kuusi, A., Kuitunen, P. et al. Childhood hyperthyroidism: results of treatment, and studies of gastric mucosa. Pediatr Res 12, 1085 (1978). https://doi.org/10.1203/00006450-197811000-00023
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DOI: https://doi.org/10.1203/00006450-197811000-00023