Abstract
The purpose of this study was to develop a scoring system which would assist in the prognosis of ALL In childhood. The following system was utilized retrospectively on the initial clinical data on 41 children with ALL who received systemic combination chemotherapy and central nervous system (CNS) therapy ± organ (liver, kidneys and spleen) irradiation.
Numerical values yielded total scores ranging from -2 to +3 for each of 41 patients. Mean scores for those who succeeded (i.e. continuous remission of at least 2½ years) was significantly different at the 0.005 level compared to those who failed (i.e. relapse or death). The implication of this is that such a scoring system (not incorporating the WBC) when used in conjunction with the white cell count may more accurately determine the prognosis of ALL in childhood.
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Shende, A., Lanzkowsky, P. & Fisichelli, V. UTILIZATION OF A SCORE SYSTEM IN THE PROGNOSIS OF ACUTE LYMPHOCYTIC LEUKEMIA (ALL) IN CHILDHOOD. Pediatr Res 11, 480 (1977). https://doi.org/10.1203/00006450-197704000-00662
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DOI: https://doi.org/10.1203/00006450-197704000-00662