Abstract
A 13-yr-old WF was admitted to the University of Miami Medical Center because of persistent vomiting for 2 months associated with weight loss of 16 pounds. Abdominal exploration and appendectomy because of 8 months of persistent abdominal pain demonstrate no abnormality. Post-operatively she developed nausea and vomiting of all oral intake. Upper GI series had shown no abnormality. Cineesophagogram and endoscopy revealed minimal esophagitis and mild pylorospasm. While in hospital on IV fluids, vomiting of all oral intake persisted. Substitution of intragastric drip feedings of sustacal R for IV fluids was associated with much improved retention temporarily with reocurrence of vomiting. Intragastric milk was tolerated, however, and other foods except for corn products were gradually added to the diet and tolerated. Intradermal provocative food testing with corn extract produced definite symptom response suggesting sensitivity to corn. IV injection of 25 ml D5/water reproduced all previous GI symptoms. A meal of corn syrup and corn meal produced nausea and vomiting 3 hours after ingestion associated with acute alteration and decreased plasma C3 complement concentration. Initial C3 was low (67 mg%), serum IgE (440 u/ml) and serum IgM (480 mg%) were elevated. Avoidance of corn products resulted in 13.5 Ib. weight gain in 3 weeks with no nausea or vomiting.
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Sandberg, D. PERSISTENT VOMITING DUE TO SENSITIVITY TO CORN SUGAR OR DEXTROSE PRESENT IN INTRAVENOUS FLUIDS. Pediatr Res 11, 449 (1977). https://doi.org/10.1203/00006450-197704000-00478
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DOI: https://doi.org/10.1203/00006450-197704000-00478