Abstract
After injection of 20.10 CPM/100 g body weight C14 palmitic acid, the primary FFA pool was in 7 days old well-fed rabbits /Group I/ 9.57±2.12 μmole, and in rabbits of the same age but previously starved for 48 hrs. at 20 C° /Group II/3.17 ±0.41 and in those starved 72 hours at 35 C° /Group III/1.89±0.50.
There was no significant difference in half time /t 1/2/ and turnover time, but turnover rate / μmole FFA/min/ was significantly diminished by starvation. /Group I.9.38±0.72, Group II. 3.44±0.49, Group III. 2.67±0.60/.
Starvation at different ambient temperatures affected FFA phospholipid and glyceride pools/μmole/100 g body weight as well as the total flux of labelled fatty acid/ μmole/min/ between the intracellular and extracellular lipid compartments of brown and white adipose tissue.
In brown adipose tissue FFA flux was in Group I.: 0.315±0.031 μmole/min, in Group II.: 0.226±0.039, in Group III: 0.047±0.008. The corresponding figures for white adipose tissue in Group I.: 0.072±0.011 μmole/min, in Group II: 0.009±0.001, in Group III.: 0.014±0.004.
Functions of the two adipose tissues will be discussed.
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Heim, T., Schenk, H., Wagner, H. et al. IN VIVO METABOLISM OF C14-LABELLED PALMITIC ACID IN BROWN AND WHITE ADIPOSE TISSUE OF WELL-FED AND STARVED NEWBORN RABBITS. Pediatr Res 8, 131 (1974). https://doi.org/10.1203/00006450-197402000-00029
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DOI: https://doi.org/10.1203/00006450-197402000-00029