Abstract
Extract: Duodenal biopsies from patients with acrodermatitis enteropathica were examined by electron microscopy and dissecting microscopy. The ultrastructural studies revealed characteristic inclusions in Paneth cells with a maximum length of 7 μm. These findings were constant in four different patients. A follow-up study in one patient showed the same alterations before and after treatment.
Speculation: The biochemical defect of acrodermatitis enteropathica is unknown and, therefore, typical ultrastructural alterations challenge one to investigate the nature of the included material.
Similar content being viewed by others
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Lombeck, I., Von Bassewitz, D., Becker, K. et al. Ultrastructural Findings in Acrodermatitis Enteropathica. Pediatr Res 8, 82–88 (1974). https://doi.org/10.1203/00006450-197402000-00003
Issue Date:
DOI: https://doi.org/10.1203/00006450-197402000-00003
Keywords
This article is cited by
-
Maintenance of Intestinal Epithelial Homeostasis by Zinc Transporters
Digestive Diseases and Sciences (2019)
-
Zinc supplementation in the treatment of childhood Diarrhoea
The Indian Journal of Pediatrics (1995)
-
Clinical and laboratory diagnosis of acrodermatitis enteropathica
European Journal of Pediatrics (1989)
-
Fatty acid composition of plasma lipids in acrodermatitis enteropathica before and after zinc supplementation
European Journal of Pediatrics (1985)
-
Acrodermatitis enteropathica
Journal of Inherited Metabolic Disease (1983)