Abstract
The conformation and intramolecular interactions in solution were investigated for the glycopeptides, Boc–Asn(GlcNAc)–OMe, Boc–Asn(GlcNAc)–Gly–OMe, and Boc–Asn(GlcNAc)–Gly–Ser–OMe with the aids of 1H NMR. There are no specific intramolecular interactions in glycopeptides and the hydrogen bond between the side chains of Asn and Ser was not found in Boc–Asn(GlcNAc)–Gly–Ser–OMe contrary to that in Boc–Asn–Gly–Ser–OMe. The side chain conformation of the triplet sequence is considerably affected by N-glycosylation.
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Ishii, H., Inoue, Y. & Chûjô, R. 1H NMR Study of Glycopeptides with the Triplet Sequence –Asn–Gly–Ser–. Polym J 17, 693–700 (1985). https://doi.org/10.1295/polymj.17.693
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DOI: https://doi.org/10.1295/polymj.17.693
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