Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Original Article
  • Published:

First-year costs of treating prostate cancer: estimates from SEER-Medicare data

Abstract

Pharmacologic therapies are currently being evaluated for the prevention of prostate cancer (PCa). As additional clinical data become available regarding their benefits and risks, an examination of their economic impact will also be important. The purpose of this study was to estimate mean per patient PCa-related costs during the first year following diagnosis and to examine the extent to which initial therapies are used, by initial cancer stage. Our data show that health-care costs were significant and varied by stage. With average first-year PCa-related costs of US$13 091, prevention strategies have the potential to reduce health-care costs.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1
Figure 2

Similar content being viewed by others

References

  1. Thompson IM, Goodman PJ, Tangen CM, Lucia MS, Miller GJ, Ford LG et al. The influence of finasteride on the development of prostate cancer. N Engl J Med 2003; 349: 215.

    Article  CAS  PubMed  Google Scholar 

  2. Redman MW, Tangen CM, Goodman PJ, Lucia MS, Coltman Jr CA, Thompson IM . Finasteride does not increase the risk of high-grade prostate cancer: a bias-adjusted modeling approach. Cancer Prev Res 2008; 1: 174.

    Article  CAS  Google Scholar 

  3. Lucia MS, Darke AK, Goodman PJ, La Rosa FG, Parnes HL, Ford LG et al. Pathologic characteristics of cancers detected in the Prostate Cancer Prevention Trial: implications for prostate cancer detection and chemoprevention. Cancer Prev Res 2008; 1: 167.

    Article  CAS  Google Scholar 

  4. Pinsky P, Parnes H, Ford L . Estimating rates of true high-grade disease in the Prostate Cancer Prevention Trial. Cancer Prev Res 2008; 1: 182.

    Article  Google Scholar 

  5. Logothetis CJ, Schellhammer PF . High-grade prostate cancer and the Prostate Cancer Prevention Trial. Cancer Prev Res 2008; 1: 151.

    Article  Google Scholar 

  6. Andriole G, Bostwick D, Brawley O, Gomella L, Marberger M, Tindall D et al. Chemoprevention of prostate cancer in men at high risk: rationale and design of the Reduction by Dutasteride of Prostate Cancer Events (REDUCE) Trial. J Urol 2004; 172: 1314.

    Article  CAS  PubMed  Google Scholar 

  7. Taplin SH, Barlow W, Urban N, Mandelson MT, Timlin DJ, Ichikawa L et al. Stage, age, comorbidity, and direct costs of colon, prostate, and breast cancer care. J Natl Cancer Inst 1995; 87: 417.

    Article  CAS  PubMed  Google Scholar 

  8. Penberthy L, Retchin SM, McDonald MK, McClish DK, Desch CE, Riley GF et al. Predictors of Medicare costs in elderly beneficiaries with breast, colorectal, lung, or prostate cancer. Health Care Manag Sci 1999; 2: 149.

    Article  CAS  PubMed  Google Scholar 

  9. Penson DF, Schonfeld WH, Flanders SC, Henke CJ, Warolin KL, Carroll PR et al. Relationship of first-year costs of treating localized prostate cancer to initial choice of therapy and stage at diagnosis: results from the CAPSURE database. Urology 2001; 57: 499.

    Article  CAS  PubMed  Google Scholar 

  10. Warren JL, Yabroff KR, Meekins A, Topor M, Lamont EB, Brown ML . Evaluation of trends in the cost of initial cancer treatment. J Natl Cancer Inst 2008; 100: 888.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Zeliadt SB, Etzioni R, Ramsey SD, Penson DF, Potosky AL . Trends in treatment costs for localized prostate cancer. Med Care 2007; 45: 154.

    Article  PubMed  Google Scholar 

  12. Brandeis J, Pashos CL, Henning JM, Litwin MS . A nationwide charge comparison of the principal treatments for early stage prostate cancer. Cancer 2000; 89: 1792.

    Article  CAS  PubMed  Google Scholar 

  13. National Cancer Institute. Surveillance, Epidemiology, and End Results: About SEER. National Cancer Institute: Bethesda, MD, 2008. Available at: http://seer.cancer.gov/about. Accessed September 2008.

  14. American Joint Committee on Cancer. Past Editions of the AJCC Cancer Staging Manual. American Joint Committee on Cancer: Chicago, 2008. Available at: http://www.cancerstaging.org/products/pasteditions.html. Accessed March 2008.

  15. Deyo RA, Cherkin DC, Ciol MA . Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol 1992; 45: 613.

    Article  CAS  Google Scholar 

  16. Efron B, Tibshirani RJ . An Introduction to the Bootstrap. Chapman and Hall: New York, 1993.

    Book  Google Scholar 

  17. Litwin MS, Pasta DJ, Stoddard ML, Henning JM, Caroll PR . Epidemiological trends and financial outcomes in radical prostatectomy among Medicare beneficiaries, 1991 to 1993. J Urol 1998; 160: 445.

    Article  CAS  PubMed  Google Scholar 

  18. Iezzoni LI . Assessing quality using administrative data. Ann Intern Med 1997; 127: 666.

    Article  CAS  PubMed  Google Scholar 

  19. Hu JC, Wang Q, Pashos CL, Lipsitz SR, Keating NL . Utilization and outcomes of minimally invasive radical prostatectomy. J Clin Oncol 2008; 26: 2278.

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

This study used the linked SEER-Medicare database. The interpretation and reporting of these data are the sole responsibility of the authors. The authors acknowledge the efforts of the Applied Research Program, National Cancer Institute; the Office of Research, Development and Information, CMS; Information Management Services, Inc.; and the Surveillance, Epidemiology, and End Results (SEER) Program tumor registries in the creation of the SEER-Medicare database. Research funding was provided by GlaxoSmithKline Inc.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to M E Stokes.

Additional information

Parts of this research were presented at American Urological Association Annual Meeting, 17–22 May 2008, Orlando, FL, USA.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Roehrborn, C., Albertsen, P., Stokes, M. et al. First-year costs of treating prostate cancer: estimates from SEER-Medicare data. Prostate Cancer Prostatic Dis 12, 355–360 (2009). https://doi.org/10.1038/pcan.2009.21

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/pcan.2009.21

Keywords

This article is cited by

Search

Quick links