Heat shock protein 90 (Hsp90) was the focus of a recent meeting in the Swiss Alps, where the Hsp90 community met to discuss the operation and functions of this ubiquitous and essential molecular chaperone.
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Structure-guided design of an Hsp90β N-terminal isoform-selective inhibitor
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References
Retzlaff, M. et al. Mol. Cell 37, 344–354 (2010).
Zhang, M., Kadota, Y., Prodromou, C., Shirasu, K. & Pearl, L.H. Mol. Cell 39, 269–281 (2010).
Ratzke, C., Mickler, M., Hellenkamp, B., Buchner, J. & Hugel, T. Proc. Natl. Acad. Sci. USA 107, 16101–16106 (2010).
Mollapour, M. et al. Mol. Cell 37, 333–343 (2010).
Zhao, R. et al. J. Cell Biol. 180, 563–578 (2008).
Walerych, D. et al. J. Biol. Chem. 285, 32020–32028 (2010).
Prahlad, V., Cornelius, T. & Morimoto, R.I. Science 320, 811–814 (2008).
Sreedhar, A.S., Kalmar, E., Csermely, P. & Shen, Y.F. FEBS Lett. 562, 11–15 (2004).
Eustace, B.K. & Jay, D.G. Cell Cycle 3, 1098–1100 (2004).
Chadli, A., Felts, S.J. & Toft, D.O. J. Biol. Chem. 283, 9509–9512 (2008).
Gaiser, A.M., Brandt, F. & Richter, K. J. Mol. Biol. 391, 621–634 (2009).
Fontana, L., Partridge, L. & Longo, V.D. Science 328, 321–326 (2010).
Ostrovsky, O., Ahmed, N.T. & Argon, Y. Mol. Biol. Cell 20, 1855–1864 (2009).
Ostrovsky, O., Makarewich, C.A., Snapp, E.L. & Argon, Y. Proc. Natl. Acad. Sci. USA 106, 11600–11605 (2009).
Taipale, M., Jarosz, D.F. & Lindquist, S. Nat. Rev. Mol. Cell Biol. 11, 515–528 (2010).
Tariq, M., Nussbaumer, U., Chen, Y., Beisel, C. & Paro, R. Proc. Natl. Acad. Sci. USA 106, 1157–1162 (2009).
Queitsch, C., Sangster, T.A. & Lindquist, S. Nature 417, 618–624 (2002).
Geller, R., Vignuzzi, M., Andino, R. & Frydman, J. Genes Dev. 21, 195–205 (2007).
Jinwal, U.K. et al. J. Neurosci. 30, 591–599 (2010).
Trepel, J., Mollapour, M., Giaccone, G. & Neckers, L. Nat. Rev. Cancer 10, 537–549 (2010).
Kim, Y.S. et al. Curr. Top. Med. Chem. 9, 1479–1492 (2009).
Davenport, E.L. et al. Targeting heat shock protein 72 enhances Hsp90 inhibitor-induced apoptosis in myeloma. Leukemia (2010).
Powers, M.V. et al. Cell Cycle 9, 1542–1550 (2010).
Prodromou, C. et al. ACS Chem. Biol. 4, 289–297 (2009).
Millson, S.H., Prodromou, C. & Piper, P.W. Biochem. Pharmacol. 79, 1581–1588 (2010).
Morimoto, R.I. & Santoro, M.G. Nat. Biotechnol. 16, 833–838 (1998).
Lu, Y., Ansar, S., Michaelis, M.L. & Blagg, B.S. Bioorg. Med. Chem. 17, 1709–1715 (2009).
Urban, M.J. et al. ASN Neuro. 2, e00040 (2010).
Donnelly, A.C. et al. Med. Chem. Commun. 1, 165–170 (2010).
Morra, G., Genoni, A., Neves, M.A., Merz, K.M. Jr. & Colombo, G. Curr. Med. Chem. 17, 25–41 (2010).
LaFayette, S.L. et al. PLoS Pathog. 6, e1001069 (2010).
Singh, S.D. et al. PLoS Pathog. 5, e1000532 (2009).
Shapiro, R.S. et al. Curr. Biol. 19, 621–629 (2009).
Pallavi, R. et al. J. Biol. Chem. published online, doi: 10.1074/jbc.M110.155317 (13 September 2010).
Shahinas, D., Liang, M., Datti, A. & Pillai, D.R. J. Med. Chem. 53, 3552–3557 (2010).
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Vaughan, C., Neckers, L. & Piper, P. Understanding of the Hsp90 molecular chaperone reaches new heights. Nat Struct Mol Biol 17, 1400–1404 (2010). https://doi.org/10.1038/nsmb1210-1400
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DOI: https://doi.org/10.1038/nsmb1210-1400
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