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Wobble during decoding: more than third-position promiscuity

Nature Structural & Molecular Biology volume 11, pages 11601162 (2004) | Download Citation

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Structural studies by the Ramakrishnan and Agris groups allow us to directly observe how the ribosome's decoding site accommodates non-Watson-Crick base pairs in the third position of the codon-anticodon triplet while maintaining the one-amino-acid-per-codon framework that is central to life.

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Author information

Affiliations

  1. Howard Hughes Medical Institute, Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. ragreen@jhmi.edu

    • Luisa Cochella
    •  & Rachel Green

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DOI

https://doi.org/10.1038/nsmb1204-1160

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