Three recent reports identify the roles of specific ribonucleases necessary for efficient termination of transcription by RNA polymerase II. In one case, the primary cleavage event is carried out by a ribozyme encoded in the pre-mRNA itself.
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The author is in the Departamento de Fisiología y Biología Molecular, LFBM and IFIByNE-CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina. ark@fbmc.fcen.uba.ar
- Alberto R Kornblihtt
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