Three recent reports identify the roles of specific ribonucleases necessary for efficient termination of transcription by RNA polymerase II. In one case, the primary cleavage event is carried out by a ribozyme encoded in the pre-mRNA itself.
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Kornblihtt, A. Shortcuts to the end. Nat Struct Mol Biol 11, 1156–1157 (2004). https://doi.org/10.1038/nsmb1204-1156
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DOI: https://doi.org/10.1038/nsmb1204-1156