A recent structural study on a human RNA deaminase reveals that inositol hexakisphosphate is a cofactor of the enzyme and is essential for its editing activity.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Decreasing undesirable absorbed radiation to the intestine after administration of radium-223 dichloride for treatment of bone metastases
Scientific Reports Open Access 17 July 2020
Access options
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Bass, B.L. Annu. Rev. Biochem. 71, 817–846 (2002).
Macbeth, M.R. et al. Science 309, 1534–1539 (2005).
Gerber, A.P. & Keller, W. Trends Biochem. Sci. 26, 376–384 (2001).
York, J.D., Odom, A.R., Murphy, R., Ives, E.B. & Wente, S.R. Science 285, 96–100 (1999).
Hawkins, P.T. et al. Biochem. J. 294, 929–934 (1993).
Shen, X., Xiao, H., Ranallo, R., Wu, W.-H. & Wu, C. Science, 299, 112–114 (2003).
Steger, D.J., Haswell, E.S., Miller, A.L., Wente, S.R. & O'Shea, E.K. Science, 299, 114–116 (2003).
Hanakahi, L.A. & West, S.C. EMBO J. 21, 2038–2044 (2002).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Scadden, D. When extreme negativity is a positive thing. Nat Struct Mol Biol 12, 940–941 (2005). https://doi.org/10.1038/nsmb1105-940
Issue Date:
DOI: https://doi.org/10.1038/nsmb1105-940