The implication of arginine methylation in mRNA biogenesis from transcription to mRNA export has been documented by various groups, but the precise role of methylation in this process is still unknown. A recent study demonstrates that in Saccharomyces cerevisiae methylation modulates the interaction and recruitment of components of the RNA packaging and export machinery.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Identification of a novel lipin homologue from the parasitic protozoan Trypanosoma brucei
BMC Microbiology Open Access 08 May 2013
Access options
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Gary, J.D. & Clarke, S. Prog. Nucleic Acid Res. Mol. Biol. 61, 65–131 (1998).
McBride, A.E. & Silver, P.A. Cell 106, 5–8 (2001).
Yu, M.C. et al. Genes Dev. 18, 2024–2035 (2004).
Dreyfuss, G., Kim, V.N. & Kataoka, N. Nat. Rev. Mol. Cell Biol. 3, 195–205 (2002).
Henry, M.F. & Silver, P.A. Mol. Cell. Biol. 16, 3668–3678 (1996).
Gary, J.D., Lin, W.J., Yang, M.C., Herschman, H.R. & Clarke, S. J. Biol. Chem. 271, 12585–12594 (1996).
Shen, E. et al. Genes Dev. 12, 679–691 (1998).
Côté, J., Boisvert, F.-M., Boulanger, M.-C., Bedford, M.T. & Richard, S. Mol. Biol. Cell 14, 274–287 (2003).
Valentini, S.R., Weiss, V.H. & Silver, P.A. RNA 5, 272–280 (1999).
An, W., Kim, J. & Roeder, R.G. Cell 117, 735–748 (2004).
Rezai-Zadeh, N. et al. Genes Dev. 17, 1019–1029 (2003).
Lee, M.S., Henry, M. & Silver, P.A. Genes Dev. 10, 1233–1246 (1996).
Siebel, C.W. & Guthrie, C. Proc. Natl. Acad. Sci. USA 93, 13641–13646 (1996).
Yun, C.Y. & Fu, X.-D. J. Cell Biol. 150, 707–717 (2000).
Gilbert, W. & Guthrie, C. Mol. Cell 13, 201–212 (2004).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Lukong, K., Richard, S. Arginine methylation signals mRNA export. Nat Struct Mol Biol 11, 914–915 (2004). https://doi.org/10.1038/nsmb1004-914
Issue Date:
DOI: https://doi.org/10.1038/nsmb1004-914
This article is cited by
-
Nuclear loss of protein arginine N-methyltransferase 2 in breast carcinoma is associated with tumor grade and overexpression of cyclin D1 protein
Oncogene (2014)
-
Identification of a novel lipin homologue from the parasitic protozoan Trypanosoma brucei
BMC Microbiology (2013)
-
Suppression of receptor interacting protein 140 repressive activity by protein arginine methylation
The EMBO Journal (2006)
