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Resolving integral questions in site-specific recombination

Nature Structural & Molecular Biology volume 12, pages 641643 (2005) | Download Citation

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Two long-awaited structures of serine and tyrosine site-specific recombinases bound to DNA show how reactions that are basically the same can be carried out in surprisingly different ways.

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References

  1. 1.

    & in Mobile DNA II (eds. Craig, N.L., Craigie, R., Gellert, M. & Lambowitz, A.M.) 12–23 (ASM Press, Washington, DC, 2002).

  2. 2.

    et al. Nature 435, 1059–1066 (2005).

  3. 3.

    et al. Science, published online 30 June 2005 (0:11120641).

  4. 4.

    & in Mobile DNA II (eds. Craig, N.L., Craigie, R., Gellert, M. & Lambowitz, A.M.) 118–148 (ASM Press, Washington, DC, 2002).

  5. 5.

    & Annu. Rev. Biophys. Biomol. Struct. 32, 135–159 (2003).

  6. 6.

    et al. Phil. Trans. R. Soc. Lond. B 359, 61–69 (2004).

  7. 7.

    in Mobile DNA II (eds. Craig, N.L., Craigie, R., Gellert, M. & Lambowitz, A.M.) 93–117 (ASM Press, Washington, DC, 2002).

  8. 8.

    Structure 6, 543–548 (1998).

  9. 9.

    , & Nature 389, 40–46 (1997).

  10. 10.

    , & Mol. Microbiol. 44, 607–619 (2002).

  11. 11.

    & Mol. Microbiol. 44, 299–307 (2002).

  12. 12.

    in Mobile DNA II (eds. Craig, N.L., Craigie, R., Gellert, M. & Lambowitz, A.M.) 272–302 (ASM Press, Washington, DC, 2002).

  13. 13.

    , & Cell 58, 779–790 (1989).

  14. 14.

    & Cell 82, 193–207 (1995).

  15. 15.

    & EMBO J. 13, 1514–1524 (1994).

  16. 16.

    & J. Mol. Biol. 340, 753–766 (2004).

Download references

Author information

Affiliations

  1. The author is in the Department of Biochemistry & Molecular Biology, University of Chicago, Chicago, Illinois 60615, USA. price@uchicago.edu

    • Phoebe A Rice

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DOI

https://doi.org/10.1038/nsmb0805-641

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