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A milestone in the odyssey of higher-order chromatin structure

Nature Structural & Molecular Biology volume 12, pages 639640 (2005) | Download Citation

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The recent crystal structure of tetra nucleosomes supports zigzag-based models of chromatin fiber structure. The next challenge is to understand the modulation of chromatin structure in the nucleus, characterized by variability in DNA, histones and non-histone components.

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Author information

Affiliations

  1. The author is in the Department of Biology, University of Massachusetts, Amherst, Massachusetts 01003, USA. chris@bio.umass.edu

    • Christopher L Woodcock

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DOI

https://doi.org/10.1038/nsmb0805-639

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