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Toward understanding GPCR dimers

Recent studies on the metabotropic glutamate receptors provide new insights into their signaling mechanisms that may apply to other G-protein coupled receptor (GPCR) families.

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Figure 1: Three structural models that could explain activation of mGluRs.

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Parnot, C., Kobilka, B. Toward understanding GPCR dimers. Nat Struct Mol Biol 11, 691–692 (2004). https://doi.org/10.1038/nsmb0804-691

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