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Moving parts: how the adaptor protein CRK is regulated, and regulates

The solution structures of multiple forms of the adaptor protein CRK show how its domains fit together, providing insight into the autoregulation and ligand-mediated regulation of CRK.

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Figure 1: Domain organization of CRK isoforms and constructs used in recent structural studies.

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Cowburn, D. Moving parts: how the adaptor protein CRK is regulated, and regulates. Nat Struct Mol Biol 14, 465–466 (2007). https://doi.org/10.1038/nsmb0607-465

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