The Mre11 protein complex plays important roles in maintaining genome stability. Inter-molecular bridging by the Rad50 protein has now been shown to be critical to this complex's function.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Wiltzius, J.J.W., Hohl, M., Fleming, J.C. & Petrini, J.H. Nat. Struct. Mol. Biol. 12, 403–407 (2005).
Assenmacher, N. & Hopfner, K.P. Chromosoma 113, 157–166 (2004).
Moore, J.K. & Haber, J.E. Mol. Cell. Biol. 16, 2164–2173 (1996).
Bressan, D.A., Baxter, B.K. & Petrini, J.H. Mol. Cell. Biol. 19, 7681–7687 (1999).
Lydall, D. J. Cell Sci. 116, 4057–4065 (2003).
Purdy, A. & Su, T.T. Curr. Biol. 14, R613–R614 (2004).
Mirzoeva, O.K. & Petrini, J.H. Mol. Cell. Biol. 21, 281–288 (2001).
Lisby, M., Barlow, J.H., Burgess, R.C. & Rothstein, R. Cell 118, 699–713 (2004).
Shroff, R. et al. Curr. Biol. 14, 1703–1711 (2004).
Nakada, D., Matsumoto, K. & Sugimoto, K. Genes Dev. 17, 1957–1962 (2003).
Falck, J., Coates, J. & Jackson, S.P. Nature 434, 605–611 (2005).
Lee, J.H. & Paull, T.T. Science published online, 24 March 2005 (10.1126/science.1108297).
Prieler, S., Penkner, A., Borde, V. & Klein, F. Genes Dev. 19, 255–269 (2005).
Connelly, J.C. & Leach, D.R. Trends Biochem. Sci. 27, 410–418 (2002).
Hopfner, K.P. et al. Cell 105, 473–485 (2001).
Hopfner, K.P. et al. Nature 418, 562–566 (2002).
Moreau, S., Ferguson, J.R. & Symington, L.S. Mol. Cell. Biol. 19, 556–566 (1999).
de Jager, M. et al. Mol. Cell 8, 1129–1135 (2001).
Anderson, D.E., Trujillo, K.M., Sung, P. & Erickson, H.P. J. Biol. Chem. 276, 37027–37033 (2001).
Costanzo, V., Paull, T., Gottesman, M. & Gautier, J. PLoS Biol. 2, e110 (2004).
Lobachev, K., Vitriol, E., Stemple, J., Resnick, M.A. & Bloom, K. Curr. Biol. 14, 2107–2112 (2004).
Rollins, C.T. et al. Proc. Natl. Acad. Sci. USA 97, 7096–7101 (2000).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Lichten, M. Rad50 connects by hook or by crook. Nat Struct Mol Biol 12, 392–393 (2005). https://doi.org/10.1038/nsmb0505-392
Issue Date:
DOI: https://doi.org/10.1038/nsmb0505-392