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Going for RNA repeats

Repeating RNA sequences often serve as protein targets during regulatory processes involving single-stranded RNA (ssRNA). New data on the HutP protein show how it is activated and binds a repeat-containing ssRNA. Together with previous work, these studies demonstrate the versatility of RNA-binding proteins in regulating transcription in bacteria.

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Figure 1: Mechanisms of transcription attenuation and antitermination.
Figure 2: HutP and TRAP “capture” the ssRNA by binding appropriately spaced trinucleotide repeats.

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Gollnick, P., Antson, A. Going for RNA repeats. Nat Struct Mol Biol 12, 289–290 (2005). https://doi.org/10.1038/nsmb0405-289

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