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Ribozyme déjà vu

Nature Structural & Molecular Biology volume 11, pages 301–303 (2004)Cite this article

A novel natural ribozyme has been discovered in the 5′ noncoding region of the glmS mRNA. Surprisingly, glmS ribozyme activity is modulated by a cellular metabolite. The glmS ribozyme thus represents the first example of an novel regulatory mechanism in bacteria.

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Figure 1: RNA-based feedback inhibition.
Figure 2: Parallels between biotechnology and nature.

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Authors and Affiliations

  1. Department of Chemistry and Biochemistry, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, 78712, Texas, USA

    Scott M Knudsen & Andrew D Ellington

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  1. Scott M Knudsen
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  2. Andrew D Ellington
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Knudsen, S., Ellington, A. Ribozyme déjà vu. Nat Struct Mol Biol 11, 301–303 (2004). https://doi.org/10.1038/nsmb0404-301

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