Analyses of telomere-binding proteins show structural and functional conservation with subunits of replication protein A, the canonical single-stranded DNA–binding protein. These studies raise intriguing questions about the structure and general role of DNA binding in telomere length homeostasis.
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References
Smogorzewska, A. & de Lange, T. Annu. Rev. Biochem. 73, 177–208 (2004).
Gao, H., Cervantes, R.B., Mandell, E.K., Otero, J.H. & Lundblad, V. Nat. Struct. Mol. Biol. 14, 208–214 (2007).
Wold, M.S. Annu. Rev. Biochem. 66, 61–92 (1997).
Croy, J.E. & Wuttke, D.S. Trends Biochem. Sci. 31, 516–525 (2006).
Grandin, N., Reed, S.I. & Charbonneau, M. Genes Dev. 11, 512–527 (1997).
Grandin, N., Damon, C. & Charbonneau, M. EMBO J. 20, 1173–1183 (2001).
Petreaca, R.C. et al. Nat. Cell Biol. 8, 748–755 (2006).
Pennock, E., Buckley, K. & Lundblad, V. Cell 104, 387–396 (2001).
Smith, J., Zou, H. & Rothstein, R. Biochimie 82, 71–78 (2000).
Schramke, V. et al. Nat. Genet. 36, 46–54 (2004).
Salas, T.R. et al. Nucleic Acids Res. 34, 4857–4865 (2006).
Philipova, D., Mullen, J.R., Maniar, H.S., Gu, C. & Brill, S.J. Genes Dev. 10, 2222–2233 (1996).
Saeki, H. et al. Proc. Natl. Acad. Sci. USA 103, 8768–8773 (2006).
Fanning, E., Klimovich, V. & Nager, A.R. Nucleic Acids Res. 34, 4126–4137 (2006).
Zubko, M.K. & Lydall, D. Nat. Cell Biol. 8, 734–740 (2006).
Henson, J.D., Neumann, A.A., Yeager, T.R. & Reddel, R.R. Oncogene 21, 598–610 (2002).
Larrivee, M. & Wellinger, R.J. Nat. Cell Biol. 8, 741–747 (2006).
Bochkarev, A., Pfuetzner, R.A., Edwards, A.M. & Frappier, L. Nature 385, 176–181 (1997).
Bochkareva, E., Korolev, S., Lees-Miller, S.P. & Bochkarev, A. EMBO J. 21, 1855–1863 (2002).
Mitton-Fry, R.M., Anderson, E.M., Theobald, D.L., Glustrom, L.W. & Wuttke, D.S. J. Mol. Biol. 338, 241–255 (2004).
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Haring, S., Wold, M. A common means to an end. Nat Struct Mol Biol 14, 176–177 (2007). https://doi.org/10.1038/nsmb0307-176
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DOI: https://doi.org/10.1038/nsmb0307-176