A recent paper reports that Spn-A is the Rad51 ortholog in Drosophila melanogaster. This and other findings in this study open the door to genetic analysis of Rad51 functions in a model metazoan.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Haber, J.E. Trends Genet. 16, 259–264 (2000).
Sung, P., Krejci, L., Van Komen, S. & Sehorn, M.G. J. Biol. Chem. 278, 42729–42732 (2003).
Symington, L.S. Micro. Mol. Biol. Rev. 66, 630–670 (2002).
Tsuzuki, T. et al. Proc. Natl. Acad. Sci. USA 93, 6236–6240 (1996).
McKee, B.D., Ren, X. & Hong, C.A. Chromosoma 104, 479–488 (1996).
Akaboshi, E., Inoue, Y. & Ryo, H. Jap. J. Genet. 69, 663–670 (1994).
Staeva-Vieira, E., Yoo, S. & Lehmann, R. EMBO J. 22, 5863–5874 (2003).
Dobens, L.L. & Raftery, L.A. Dev. Dyn. 218, 80–93 (2000).
Morris, J. & Lehmann, R. Curr. Biol. 9, R55–58 (1999).
Ghabrial, A., Ray, R.P. & Schüpbach, T. Genes Dev. 12, 2711–2723 (1998).
Abdu, U., Gonzalez-Reyes, A., Ghabrial, A. & Schupbach, T. Genetics 165, 197–204 (2003).
Thacker, J. Trends Genet. 15, 166–168 (1999).
Masson, J.Y. & West, S.C. Trends Biochem. Sci. 26, 131–136 (2001).
Sekelsky, J.J., Brodsky, M.H. & Burtis, K.C. J. Cell Biol. 150, F31–F36 (2000).
Li, Z., Golub, E.I., Gupta, R. & Radding, C.M. Proc. Natl. Acad. Sci. USA 94, 11221–11226 (1997).
Bishop, D.K., Park, D., Xu, L. & Kleckner, N. Cell 69, 439–456 (1992).
Yoshida, K. et al. Mol. Cell 1, 707–718 (1998).
Hunter, N. Mol. Cell 12, 533–535 (2003).
Thompson, J.D., Gibson, T.J., Plewniak, F., Jeanmougin, F., & Higgins, D.G. Nucleic Acids Res. 25, 4876–4882 (1997).
Page, R.D.M. Comp. Appl. Biosci. 12, 357–358 (1996).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Radford, S., Sekelsky, J. Taking Drosophila Rad51 for a SPiN. Nat Struct Mol Biol 11, 9–10 (2004). https://doi.org/10.1038/nsmb0104-9
Issue Date:
DOI: https://doi.org/10.1038/nsmb0104-9
This article is cited by
-
spn-A/rad51 mutant exhibits enhanced genomic damage, cell death and low temperature sensitivity in somatic tissues
Chromosoma (2021)
-
Theatspo11-1 mutation rescues atxrcc3 meiotic chromosome fragmentation
Plant Molecular Biology (2004)