Ribosome origami

Assembly of the small ribosomal subunit from an RNA strand and 33 proteins is an intricate and dynamic process. Two cryo-EM studies now provide insight into a complicated complex of at least 51 trans-factors that act on the preribosomal small subunit to sequentially fold it into a 3D molecular machine.

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Figure 1: Dissecting the small ribosomal subunit processome.

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Correspondence to Alexey Amunts.

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Rorbach, J., Aibara, S. & Amunts, A. Ribosome origami. Nat Struct Mol Biol 24, 879–881 (2017). https://doi.org/10.1038/nsmb.3497

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