Forceful unfolding by entropic pulling is the general mechanism by which Hsp70 and Hsp110 chaperones control the oligomeric states, structures and activities of cellular proteins.
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De Los Rios, P., Goloubinoff, P. Hsp70 chaperones use ATP to remodel native protein oligomers and stable aggregates by entropic pulling. Nat Struct Mol Biol 23, 766–769 (2016). https://doi.org/10.1038/nsmb.3283
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DOI: https://doi.org/10.1038/nsmb.3283
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