Direct time-resolved single-molecule observations of promoter search by Escherichia coli RNA polymerase indicate no evidence of facilitated diffusion, according to a new report.
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Acknowledgements
Research on transcription in the authors' laboratory is supported by the US National Institutes of Health.
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Svetlov, V., Nudler, E. Looking for a promoter in 3D. Nat Struct Mol Biol 20, 141–142 (2013). https://doi.org/10.1038/nsmb.2498
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DOI: https://doi.org/10.1038/nsmb.2498
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