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Enforcing silencing: dynamic HP1 complexes in Neurospora

Abstract

Analysis of the Neurospora crassa chromodomain protein CDP-2, a component of a newly characterized HP1-containing complex, reveals a second gene-silencing mechanism and provides insights into the dynamic nature of chromatin domains that possess shared components.

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Figure 1: Diagram of the dynamic changes among chromatin domains possessing shared factors in different genetic backgrounds.

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Correspondence to Sarah C R Elgin.

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Wallrath, L., Elgin, S. Enforcing silencing: dynamic HP1 complexes in Neurospora. Nat Struct Mol Biol 19, 465–467 (2012). https://doi.org/10.1038/nsmb.2291

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