Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Leucines on a roll

Nature Structural Biology volume 3, pages 977–980 (1996)Cite this article

An Erratum to this article was published on 01 April 1997

Several proteins have recently been found to consist of repetitive structural units in a superhelical arrangement. The structure of the leucine-rich repeat variant protein represents an unexpected addition to the list of such proteins, with the repetitive unit consisting of antiparallel α- and 310-helices.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Bernstein, F.C. et al. J. Mol. Biol. 112, 535–542 (1977).

    Article  CAS  Google Scholar 

  2. Peters, J.W., Stowel, M.H.B. & Rees, D.C. Nature Struct. Biol. 3, 991–994 (1996).

    Article  CAS  Google Scholar 

  3. Barlow, D.J. & Thornton, J.M. J. Mol. Biol. 201, 601–619 (1988).

    Article  CAS  Google Scholar 

  4. Raag, R., Appelt, K., Xuong, N.-H. & Banaszak, L. J. Mol. Biol. 200, 553–569 (1988).

    Article  CAS  Google Scholar 

  5. Thunnissen, A.-M.W.H. et al. Nature 367, 750–753 (1994).

    Article  CAS  Google Scholar 

  6. Baumann, U., Wu, S., Flaherty, K.M. & McKay, D.B. EMBO J. 12, 3357–3364 (1993).

    Article  CAS  Google Scholar 

  7. Yoder, M.D., Keen, N.T. & Jurnak, F. Science 260, 1503–1507 (1993).

    Article  CAS  Google Scholar 

  8. Wallace, B.A. & Ravikumar, K. Science 241, 182–187 (1988).

    Article  CAS  Google Scholar 

  9. Langs, D.A. Science 241, 188–191 (1988).

    Article  CAS  Google Scholar 

  10. Baumann, U. J. Mol. Biol. 242, 244–251 (1994).

    Article  CAS  Google Scholar 

  11. Hamada, K. et al. J. Biochem. 119, 844–851 (1996).

    Article  CAS  Google Scholar 

  12. Yoder, M.D., Lietzke, S.E. & Jurnak, F. Structure 1, 241–251 (1993).

    Article  CAS  Google Scholar 

  13. Pickersgill, R., Jenkins, J., Harris, G., Nasser, W. & Robert-Baudouy, J. Nature Struct. Biol. 1, 717–723 (1994).

    Article  CAS  Google Scholar 

  14. Steinbacher, S. et al. Science 265, 383–386 (1994).

    Article  CAS  Google Scholar 

  15. Emsley, P., Charles, I.G., Fairweather, N.F. & Isaacs, N.W. Nature 381, 90–92 (1996).

    Article  CAS  Google Scholar 

  16. Raetz, C.R.H. & Roderick, S.L. Science 270, 997–1000 (1995).

    Article  CAS  Google Scholar 

  17. Kisker, C., Schindelin, H., Alber, B.E., Ferry, J.G. & Rees, D.C. EMBO J. 15, 2323–2330 (1996).

    Article  CAS  Google Scholar 

  18. Kobe, B. & Deisenhofer, J. Nature 366, 751–756 (1993).

    Article  CAS  Google Scholar 

  19. Banner, D.W. et al. Nature 255, 609–614 (1975).

    Article  CAS  Google Scholar 

  20. King, J., Haase-Pettingel, C., Robinson, A.S., Speed, M. & Mitraki, A. FASEB J. 10, 57–66 (1996).

    Article  CAS  Google Scholar 

  21. Campbell, I.D. & Downing, A.K. Trends Biotech. 12, 168–172 (1994).

    Article  CAS  Google Scholar 

  22. Delepelaire, P. & Wandersman, C. J. Biol. Chem. 264, 9083–9089 (1989).

    CAS  PubMed  Google Scholar 

  23. Delepelaire, P. & Wandersman, C. J. Biol. Chem. 265, 17118–17125 (1990).

    CAS  PubMed  Google Scholar 

  24. Duong, F., Lazdunski, A., Cami, B. & Murgier, M. Gene 121, 47–54 (1992).

    Article  CAS  Google Scholar 

  25. Dicker, I.B. & Seetharam, S. Mol. Microbiol. 6, 817–823 (1992).

    Article  CAS  Google Scholar 

  26. Vuorio, R., Harkonen, T., Tolvanen, M. & Vaara, M. FEBS Lett. 337, 289–292 (1994).

    Article  CAS  Google Scholar 

  27. Takahashi, N., Takahashi, Y. & Putnam, F.W. Proc. Natl. Acad. Sci. USA 82, 1906–1910 (1985).

    Article  CAS  Google Scholar 

  28. Kobe, B. & Deisenhofer, J. Trends Biochem. Sci. 19, 415–421 (1994).

    Article  CAS  Google Scholar 

  29. Kobe, B. & Deisenhofer, J. Curr. Opin. Struct. Biol. 5, 409–416 (1995).

    Article  CAS  Google Scholar 

  30. Kajava, A.V., Vassart, G. & Wodak, S.J. Structure 3, 867–877 (1995).

    Article  CAS  Google Scholar 

  31. Jiang, X., Dreano, M., Buckler, D.R. et al. Structure 3, 1341–1353 (1995).

    Article  CAS  Google Scholar 

  32. Moyle, W.R. et al. J. Biol. Chem. 270, 20020–20031 (1995).

    Article  CAS  Google Scholar 

  33. Yoder, M.D. & Jurnak, F. FASEB J. 9, 335–342 (1995).

    Article  CAS  Google Scholar 

  34. Jacobson, M.R. et al. J. Bacteriol. 171, 1017–1027 (1989).

    Article  CAS  Google Scholar 

  35. Windisch, J.M., Marksteiner, R. & Schneider, R. J. Biol. Chem. 270, 28133–28138 (1995).

    Article  CAS  Google Scholar 

  36. Windisch, J.M., Marksteiner, R., Lang, M.E., Auer, B. & Schneider, R. Biochemistry 34, 11256–11263 (1995).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. St. Vincent's Institute of Medical Research, 41 Victoria Parade, Fitzroy, Victoria, 3065, Australia

    Bostjan Kobe

Authors
  1. Bostjan Kobe
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kobe, B. Leucines on a roll. Nat Struct Mol Biol 3, 977–980 (1996). https://doi.org/10.1038/nsb1296-977

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nsb1296-977

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing