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Tom40: more than just a channel

Nature Structural & Molecular Biology volume 10, pages 981–982 (2003)Cite this article

The protein Tom40 is the main component of the outer membrane translocation machinery for mitochondrial preproteins. A new study extends the understanding of the molecular function of Tom40, suggesting that the pore-forming protein may interact with unfolded preprotein segments to protect against aggregation.

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Figure 1: Schematic representation of the mitochondrial outer membrane translocation system for preproteins.

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  1. Institute for Biochemistry and Molecular Biology, University of Freiburg, Hermann-Herder-Str. 7, Freiburg, D-79104, Germany

    Wolfgang Voos

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  1. Wolfgang Voos
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Voos, W. Tom40: more than just a channel. Nat Struct Mol Biol 10, 981–982 (2003). https://doi.org/10.1038/nsb1203-981

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