The structure of the Rad53p FHA domain reveals a new fundamental mechanism governing phosphothreonine-dependent protein–protein interactions in nuclear processes including DNA repair and replication in a broad range of organisms.
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Acknowledgements
I thank S.P. Jackson and S.J. Smerdon for providing the FHA1 domain coordinates, and A. Farooq and K.S. Yan for helping with figure preparation and discussion.
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Zhou, MM. Phosphothreonine recognition comes into focus. Nat Struct Mol Biol 7, 1085–1087 (2000). https://doi.org/10.1038/81919
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DOI: https://doi.org/10.1038/81919
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