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The cyclooxygenase-2 stucture: new drugs for an old target?

Nature Structural Biology volume 3, pages 897–901 (1996)Cite this article

The crystal structure of human cyclooxygenase-2 offers a unique opportunity for the design of new nonsteroidal anti-inflammatory drugs and may also provide insights into the mechanisms of membrane protein targeting and the role of prostaglandin physiology in inflammation and disease.

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Authors and Affiliations

  1. Department of Biochemistry, Michigan State University, East Lansing, Michigan, 48824-1319, USA

    R. Michael Garavito

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  1. R. Michael Garavito
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Garavito, R. The cyclooxygenase-2 stucture: new drugs for an old target?. Nat Struct Mol Biol 3, 897–901 (1996). https://doi.org/10.1038/nsb1196-897

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