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Dawdling polymerases allow introns time to splice

Nature Structural & Molecular Biology volume 10, pages 876–878 (2003)Cite this article

Two recent reports show that the rate of transcription elongation affects splice site selection and exon skipping and, thereby, the nature of the information expressed from a gene.

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Figure 1: Splice site selection is affected by the rate of RNA polymerase II (Pol II) and the abundance of splicing factors.

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Authors and Affiliations

  1. Sir William Dunn School of Pathology, University of Oxford, Oxford, UK

    Nick J Proudfoot

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  1. Nick J Proudfoot
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Proudfoot, N. Dawdling polymerases allow introns time to splice. Nat Struct Mol Biol 10, 876–878 (2003). https://doi.org/10.1038/nsb1103-876

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