Abstract
Protein purification efforts for structural genomics will focus on automation for the readily-expressed proteins, and process development for the more difficult ones, such as membrane proteins. Thousands of proteins are expected to be produced in the next few years. The purified proteins will be valuable reagents for the entire research community.
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Acknowledgements
The authors would like to acknowledge the research support of the Ontario government, the University of Toronto and the Ontario Cancer Institute. A.M.E. and C.H.A. are Scientists of the Canadian Institutes of Health Research (CIHR). J.F.G. is a Distinguished Scientist of the CIHR and a Foreign Investigator of the Howard Hughes Medical Institute. D.C. was supported by a Best Fellowship.
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Edwards, A., Arrowsmith, C., Christendat, D. et al. Protein production: feeding the crystallographers and NMR spectroscopists . Nat Struct Mol Biol 7 (Suppl 11), 970–972 (2000). https://doi.org/10.1038/80751
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DOI: https://doi.org/10.1038/80751
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