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Complexity in proteins

Low-temperature laser experiments provide insight into the rough energy landscape of myoglobin, strengthen the evidence for a hierarchical organization of the protein, and allow tantalizing glimpses into the dynamics of proteins.

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References

  1. Complexity. Cowan, G.A., Pines, D. & Meltzer, D. (Eds. Addison-Wesley) (Reading, Massacussetts; 1994).

    Google Scholar 

  2. Maddox, J. Nature 209, 376 (1995).

    Google Scholar 

  3. Thorn-Leeson, D. & Wiersma, D.A. Nature struct. Biol. 2, 849–852 (1995).

    Google Scholar 

  4. Austin, R.H., Beeson, K.W., Eisenstein, L. & Frauenfelder, H. Biochemistry 14, 5355–5373 (1975).

    Article  CAS  Google Scholar 

  5. Frauenfelder, H., Petsko, G.A. & Tsernoglou, D. Nature 280, 558–563 (1979).

    Article  CAS  Google Scholar 

  6. Frauenfelder, H., Parak, F. & Young, R.D. A. Rev. Biophys. Chem. 17, 451–479 (1988).

    Article  CAS  Google Scholar 

  7. Ansari, A. et al. Proc. natn. Acad. Sci. U.S.A. 82, 5000–5004 (1985).

    Article  CAS  Google Scholar 

  8. Friedrich, J. Meth. Enzymol. 246, 226–259 (1995).

    Article  CAS  Google Scholar 

  9. Gafert, J., Pschierer, H. & Friedrich, J. Phys. Rev. Lett. 74, 3704–3707 (1995).

    Article  CAS  Google Scholar 

  10. Frauenfelder, H., Steinbach, P.J. & Young, R.D. Chemica Scripta 29A, 145–150 (1989).

    CAS  Google Scholar 

  11. Quillin, M.L. et al. J. molec. Biol. 245, 416–436 (1995).

    Article  CAS  Google Scholar 

  12. Young, R.D. et al. Chemical Phys. 158, 315–327 (1991).

    Article  CAS  Google Scholar 

Download references

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Frauenfelder, H. Complexity in proteins. Nat Struct Mol Biol 2, 821–823 (1995). https://doi.org/10.1038/nsb1095-821

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