Low-temperature laser experiments provide insight into the rough energy landscape of myoglobin, strengthen the evidence for a hierarchical organization of the protein, and allow tantalizing glimpses into the dynamics of proteins.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Complexity. Cowan, G.A., Pines, D. & Meltzer, D. (Eds. Addison-Wesley) (Reading, Massacussetts; 1994).
Maddox, J. Nature 209, 376 (1995).
Thorn-Leeson, D. & Wiersma, D.A. Nature struct. Biol. 2, 849–852 (1995).
Austin, R.H., Beeson, K.W., Eisenstein, L. & Frauenfelder, H. Biochemistry 14, 5355–5373 (1975).
Frauenfelder, H., Petsko, G.A. & Tsernoglou, D. Nature 280, 558–563 (1979).
Frauenfelder, H., Parak, F. & Young, R.D. A. Rev. Biophys. Chem. 17, 451–479 (1988).
Ansari, A. et al. Proc. natn. Acad. Sci. U.S.A. 82, 5000–5004 (1985).
Friedrich, J. Meth. Enzymol. 246, 226–259 (1995).
Gafert, J., Pschierer, H. & Friedrich, J. Phys. Rev. Lett. 74, 3704–3707 (1995).
Frauenfelder, H., Steinbach, P.J. & Young, R.D. Chemica Scripta 29A, 145–150 (1989).
Quillin, M.L. et al. J. molec. Biol. 245, 416–436 (1995).
Young, R.D. et al. Chemical Phys. 158, 315–327 (1991).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Frauenfelder, H. Complexity in proteins. Nat Struct Mol Biol 2, 821–823 (1995). https://doi.org/10.1038/nsb1095-821
Published:
Issue Date:
DOI: https://doi.org/10.1038/nsb1095-821
This article is cited by
-
The energy landscape in non-biological and biological molecules
Nature Structural Biology (1998)
-
Polychronous kinetics with nonstationary rate constants. Effect of a medium
Russian Chemical Bulletin (1997)