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Structural basis of allosteric changes in the GroEL mutant Arg197→Ala

Nature Structural Biology volume 4, pages 690694 (1997) | Download Citation

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Combined kinetic and cryo-EM analysis of the R197A mutant of GroEL provides insight into the allosteric switching of GroEL, which is at the heart of the chaperonin mechanism.

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Author information

Affiliations

  1. Crystallography Department, Birkbeck College, Malet St, London WC117HX, UK.

    • Helen E. White
    • , Shaoxia Chen
    • , Alan M. Roseman
    •  & Helen R. Saibil
  2. Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100 Israel.

    • Ofer Yifrach
    •  & Amnon Horovitz
  3. h.saibilQmail.cryst.bbk.ac.uk

    • Helen R. Saibil

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DOI

https://doi.org/10.1038/nsb0997-690

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