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Illuminating crystallography

Nature Structural Biology volume 5, pages 627–630 (1998)Cite this article

Abstract

Synchrotron radiation is an established tool in macromolecular crystallograpghy. Its high intensity and tunability play crucial roles in many structural analysis.

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Figure 1: A diffraction pattern from a crystal of the core particle of blue-tongue virus, BTV 10, recorded on the high brilliance beamline ID2 at the ESRF.
Figure 2: Harker section v = 1/2 of the anomalous difference Patterson synthesis for a mannanase platinum derivative at 1.65 Å resolution.
Figure 3: a, The structure of a complex between cellulase CelA from Clostridium thermocellum and cellopentaose has been refined to 0.94 Å resolution (D.M.A. Guerin & P. Alzari, manuscript in preparation).

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Acknowledgements

This brief overview is somewhat subjective and based largely on my own experience at the European Molecular Biology Laboratory Hamburg Outstation. I am greatly indebted to D. Blow who first suggested my move to Hamburg and to L. Phillipson who so strongly supported the activities there.

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  1. the Department of Chemistry University of York, York , YO1 5DD,, UK

    Keith S. Wilson

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  1. Keith S. Wilson
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Wilson, K. Illuminating crystallography. Nat Struct Mol Biol 5 (Suppl 8), 627–630 (1998). https://doi.org/10.1038/1318

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