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Converging on proline: the mechanism of WW domain peptide recognition

Nature Structural Biology volume 7, pages 611–613 (2000)Cite this article

Two new structures reveal the general rules of proline-rich motif recognition by WW domains and show that they are strikingly similar to those used by SH3 domains.

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Figure 1: WW domains use a mechanism of proline-rich peptide recognition similar to that of SH3 domains.
Figure 2: Specificity determinants in WW domain recognition.

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Authors and Affiliations

  1. the Department of Cellular and Molecular Pharmacology, Department of Biochemistry and Biophysics, and Program in Biological Sciences, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, 94143-0450, California, USA

    Ali Zarrinpar & Wendell A. Lim

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  1. Ali Zarrinpar
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  2. Wendell A. Lim
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Correspondence to Wendell A. Lim.

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Zarrinpar, A., Lim, W. Converging on proline: the mechanism of WW domain peptide recognition. Nat Struct Mol Biol 7, 611–613 (2000). https://doi.org/10.1038/77891

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