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Drug or tool, design or serendipity?

Nature Structural Biology volume 2, pages 429–432 (1995)Cite this article

Iterative protein structure-based ligand design has led to a ‘selective’ inhibitor of human non-pancreatic secretory phospholipase A2 which provides a new tool for probing metabolic pathways and may lead to a useful drug.

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Authors and Affiliations

  1. Biomolecular Structure Center, and Department of Biological Structure, University of Washington, Box 357420, Seattle, Washington, 98195–7420, USA

    Christophe L.M.J. Verlinde

  2. Laboratory of Biophysical Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands

    Bauke W. Dijkstra

Authors
  1. Christophe L.M.J. Verlinde
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  2. Bauke W. Dijkstra
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Verlinde, C., Dijkstra, B. Drug or tool, design or serendipity?. Nat Struct Mol Biol 2, 429–432 (1995). https://doi.org/10.1038/nsb0695-429

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