Cofilin, a ubiquitous 15,000 Mr protein, plays a central role in regulating cytoskeletal dynamics. Cofilin binds to act in monomers and filaments, and has a pH-dependent actin severing activity. The structure will allow for a detailed analysis of cof ilin function.
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Fedorov, A., Lappalainen, P., Fedorov, E. et al. Structure determination of yeast cofilin. Nat Struct Mol Biol 4, 366–369 (1997). https://doi.org/10.1038/nsb0597-366
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DOI: https://doi.org/10.1038/nsb0597-366
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